Maternal and Cord Blood Adiponectin Multimeric Forms in Gestational DiabetesMellitus A prospective analysis
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چکیده
RESEARCH DESIGN AND METHODSdTwo hundred and twelve women with a singleton pregnancy, 132 with NGT and 80 with GDM, and their offspring were studied. Maternal blood was obtained in the early third trimester and cord blood was obtained at delivery. Total adiponectin and the multimeric forms of adiponectin were determined in cord blood and maternal serum. Spearman rank correlation and stepwise linear correlation analysis were used to assess the relationship between cbAdiponectin levels and clinical and analytical parameters.
منابع مشابه
Maternal and Cord Blood Adiponectin Multimeric Forms in Gestational Diabetes Mellitus
OBJECTIVE To analyze the relationship between maternal adiponectin (mAdiponectin) and cord blood adiponectin (cbAdiponectin) multimeric forms (high molecular weight [HMW], medium molecular weight [MMW], and low molecular weight [LMW]) in a cohort of gestational diabetes mellitus (GDM) and normal glucose-tolerant (NGT) pregnant women. RESEARCH DESIGN AND METHODS A total of 212 women with a sin...
متن کاملرابطه وزن تولد با لپتین و آدیپونکتین
Background: Adiponectin and leptin are hormones which are related to body fat tissues and body weight. In pregnant women, conflicting associations have been reported between the role of serum concentrations of adiponectin and leptin with infant birth weight. The aim of this study was to determine the association between maternal and cord blood adiponectin and leptin concentrations with birth w...
متن کاملMaternal and cord blood adiponectin levels in relation to post-natal body size in infants in the first year of life: a prospective study
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متن کاملسطوح لپتین و آدیپونکتین خون وریدی بند ناف و مادر در نوزادان با محدودیت رشد داخل رحمی در مقایسه با نوزادان با وزن طبیعی
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متن کاملAdiponectin and leptin in maternal serum, cord blood, and breast milk.
BACKGROUND The presence of the adipokines adiponectin and leptin in cord blood and placental and fetal tissues suggests a possible role in fetal development. METHODS We measured concentrations of adiponectin and leptin in maternal serum, cord blood, and breast milk and examined their correlations within a large, population-based study. Between November 2000 and November 2001, we recruited all...
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تاریخ انتشار 2011